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(4 replies, posted in Guitars and accessories)

So running a Mexican fat Stratocaster through a solid state Fender amp with brand new cables. No effects pedals. I get a bad noise when the pickup selector is in between neck and middle, or between middle and humbucker pickup.  Also there when I go to humbucker only.
It's worse in overdrive.
Thoughts?
It's a real problem on stage between songs. 
Assistance would be appreciated.