Strings are very subjective, with everyone having their favorites because of playing style, musical taste, price, etc. I personally like Elixir NanoWeb 80/20 Bronze 12-53's on a spruce-top acoustic. They have a rich, full-bodied sound which suits my flat-picking style, and the coating allows them to keep their tone longer than uncoated strings. If you talk to a knowledgeable person at a reputable music store, they'll ask you about your instrument and playing style, and should be able to make a good recommendation. Beyond that, don't be afraid to experiment with different types until you find what you like.
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